Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gcdHglutaryl-CoA dehydrogenase; Identified by match to PFAM protein family HMMPF00441; High confidence in function and specificity. (388 aa)    
Predicted Functional Partners:
fadB-2
(fatty oxidation complex alpha subunit, enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase) identified by sequence similarity; putative InterPro: enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase; Family membership.
 
 0.979
fadB2
Fatty oxidation complex; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 0.979
fadA1
acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.941
fadA2
3-oxoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 0.941
fadA3
3-ketoacyl-CoA thiolase; Identified by match to PFAM protein family HMMPF00108 InterPro: thiolase family protein; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.941
sucB
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
   
  0.917
lpdG
(2-oxoglutarate dehydrogenase lipoamidedehydrogenase component) identified by sequence similarity; putative catalytic activity: dihydrolipoamide + nad(+) = lipoamide + nadh; High confidence in function and specificity.
   
 
  0.915
ABO_1772
InterPro: Acyl-CoA dehydrogenase pae:PA4435; Function unclear.
  
  
 
0.915
ABO_1264
acyl-CoA dehydrogenase; (acdA) identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; Specificity unclear.
  
  
 
0.908
ABO_2533
(acyl-CoA dehydrogenase, putative) identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity.
  
  
 
0.907
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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