Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
accAacetyl-CoA carboxylase; Identified by match to TIGR protein family HMMTIGR00514 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity. (651 aa)    
Predicted Functional Partners:
accD
Acetyl-CoA carboxylase; Identified by sequencesimilarity; putative InterPro: Carboxyl transferase family; High confidence in function and specificity.
 0.999
ABO_1239
(Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta), putative) identified by sequencesimilarity; putative InterPro: Carboxyl transferase family; High confidence in function and specificity.
 0.989
ech2
(enoyl-CoA hydratase/isomerase FadB1x) identified by sequence similarity; putative InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
 0.966
oadA
Oxaloacetate decarboxylase, alpha subunit; Identified by match to PFAM protein family HMMPF03721 InterPro: HMG-CoA Lyase-like family; High confidence in function and specificity.
 
 
0.958
ABO_0988
acyl-CoA dehydrogenase; Identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; Family membership.
  
 0.939
uahA
Urea carboxylase/allophanate hydrolase; Urea carboxylase; urease (ATP-hydrolysing); urea amidolyase/allophanate hydrolase [EC:6.3.4.6 3.5.1.54] identified by sequence similarity; putative InterPro: DUF183; Family membership.
  
 
 0.842
ABO_2506
(amidase family protein, putative) identified by sequencesimilarity; putative InterPro: Amidase; Family membership.
    
 0.837
accD-2
acetyl-CoA carboxylase, carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.832
birA
biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.762
accA-2
acetyl-CoA carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 
 0.728
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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