STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfjBNicotinamide adenine dinucleotide kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (300 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.945
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.933
cobB
Identified by match to PFAM protein family HMMPF02146 InterPro: Sir2 family; High confidence in function and specificity; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.921
ABO_1328
Oxidoreductase; Ocidoredutase (acting on NADH or NADPH with NAD+ or NADP+ as acceptor); Family membership.
     
 0.912
pntA
Pyridine nucleotide transhydrogenase A subunit; (transcriptional regulator LysR family) identified by match to PFAM protein family HMMPF03466 InterPro: Alanine dehydrogenase and pyridine nucleotide transhydrogenase; High confidence in function and specificity.
     
 0.911
suhB
(myo-inositol-1(or 4)-monophosphatase (extragenic suppressor protein SuhB)) identified by sequence similarity; putative InterPro: Inositol monophosphatase; High confidence in function and specificity.
 
    0.908
sth
(soluble pyridine nucleotide transhydrogenase) identified by sequence similarity; putative InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity.
     
 0.905
pntB
Pyridine nucleotide transhydrogenase, B subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.904
ABO_1228
NADH pyrophosphatase, putative; Identified by sequence similarity; putative InterPro: NUDIX hydrolase; Specificity unclear.
     
 0.901
ABO_1622
(MazG nucleotide pyrophosphohydrolase domain family protein) identified by match to TIGR protein family HMMTIGR00444 InterPro: MazG family protein; Function unclear.
     
 0.901
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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