STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pepN(aminopeptidase N, alpha-aminoacylpeptide hydrolase) identified by sequence similarity; putative InterPro: Aminopeptidase N APN (CD13); High confidence in function and specificity. (878 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.946
gshA
(glutamate-cysteine ligase) identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.921
gshB
Glutathione synthetase; Identified by match to TIGR protein family HMMTIGR01380 InterPro: Prokaryotic glutathione synthetase ATP-binding domain; High confidence in function and specificity; Belongs to the prokaryotic GSH synthase family.
    
 0.909
ggt
Gamma-glutamyltransferase precursor; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01019 InterPro: Gamma-glutamyltranspeptidase; High confidence in function and specificity.
     
 0.901
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.859
cysK
(cysteine synthase A, O-acetylserine sulfhydrylase A, O- acetylserine (thiol)-lyase A, sulfate starvation-induced protein 5) identified by sequencesimilarity; putative InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 0.821
aspC
(aspartate aminotransferase, transaminase A) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00155 InterPro: Aminotransferases class-I; High confidence in function and specificity.
     
 0.801
fusA
Elongation factor (EF); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.518
ABO_0997
Conserved hypothetical protein.
  
    0.492
ABO_0996
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.470
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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