Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (368 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.993
pyrC-3
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
 
 
 0.986
pyrC-2
Dihydroorotase, multifunctional complex type; Identified by sequencesimilarity; putative InterPro: Dihydroorotase multifunctional complex type; Hypothetical protein.
 
 0.981
pyrC
(dihydroorotase multifunctional complex type; DHOase) identified by sequencesimilarity; putative InterPro: Dihydroorotase multifunctional complex type; High confidence in function and specificity.
  
 0.978
ABO_2315
Oxidoreductase iron-sulfur-binding identified by match to PFAM protein family HMMPF00970; Family membership.
  
 
 0.976
carB
(carbamoyl-phosphate synthase large subunit, carbamoyl- phosphate synthetase ammonia chain) identified by sequence similarity; putative identified by match to PFAM protein families HMMPF02786 and HMMPF00289 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity.
 
 
 0.968
pyrB
Aspartate carbamoyltransferase; Identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.955
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.936
carA
(carbamoyl-phosphate synthase small subunit, carbamoyl-phosphate synthetase glutamine chain) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00988; putative InterPro: Glutamine amidotransferase class-I; High confidence in function and specificity; Belongs to the CarA family.
 
  
 0.920
pheT
Phenylalanyl-tRNA synthetase, beta subunit; Identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.805
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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