STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagZBeta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (345 aa)    
Predicted Functional Partners:
ABO_2044
Conserved hypothetical protein.
 
  
 0.940
ABO_1019
Conserved hypothetical protein; Identified by sequencesimilarity; putative InterPro: Uncharacterized protein family UPF0003.
       0.813
hpt
Hypoxanthine phosphoribosyltransferase; Identified by sequence similarity; putative InterPro: Phosphoribosyl transferase; High confidence in function and specificity.
       0.813
deoD
Nucleoside phosphorylase, putative; (heat shock protein putative) identified by sequence similarity; putative InterPro: Purine and other phosphorylases family 2; High confidence in function and specificity.
       0.813
erfK
Conserved hypothetical protein.
       0.800
anmK
Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
   
 0.695
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
    
 0.693
ABO_0809
Conserved hypothetical protein; Identified by sequence similarity; putative.
 
  
 0.632
mlp
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-m eso-diamino; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
 
   
 0.545
ABO_1022
(metal ion transporter putative) identified by match to PFAM protein family HMMPF03471 InterPro: Domain of unknown function DUF21; Family membership.
       0.533
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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