STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
exbD1InterPro: Biopolymer transport protein ExbD/TolR; Specificity unclear. (141 aa)    
Predicted Functional Partners:
exbB1
MotA/TolQ/ExbB proton channel family protein identified by match to PFAM protein family HMMPF01618; High confidence in function and specificity.
 
 
 0.984
tolQ
Biopolymer transport protein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.939
tonB
TonB; Periplasmic protein TonB, links inner and outer membranes; Family membership.
 
 
 0.891
tonB2
Ferric siderophore transport system,periplasmicbinding prot; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.884
exbB2
Identified by match to PFAM protein family HMMPF01618 InterPro: MotA/TolQ/ExbB proton channel family; High confidence in function and specificity.
 
 
 0.851
lpxK
Tetraacyldisaccharide 4`-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
    0.841
msbA
ATP-binding cassette (ABC) LPS transporter,permease; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
     
 0.831
rec2
(DNA internalization-related competence protein ComEC/Rec2) identified by match to PFAM protein family HMMPF03772 InterPro: DNA internalization-related competence protein ComEC/Rec2 Possibly exported; Family membership.
       0.727
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.656
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
   
   0.605
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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