Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mltGConserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (352 aa)    
Predicted Functional Partners:
dsbD-2
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
  
 0.984
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
      0.910
tatD
Deoxyribonuclease, TatD family; Identified by match to PFAM protein family HMMPF01026 InterPro: Uncharacterized protein family UPF0006; Family membership.
    
 0.900
holB
DNA polymerase III, delta prime subunit; High confidence in function and specificity.
  
  
 0.881
pabC
4-amino-4-deoxychorismate lyase; Identified by sequence similarity; putative InterPro: Aminotransferases class-IV; High confidence in function and specificity.
  
  
 0.863
mrcB
Penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
   
 0.841
fabF
3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
      0.836
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by sequencesimilarity; putative InterPro: Acyl transferase domain; High confidence in function and specificity.
    
 0.756
pilZ
Type IV pilus biogenesis protein, identified by sequence similarity to Pseudomonas syringae pv. tomato str. DC3000; High confidence in function and specificity.
       0.696
mtgA
Peptidoglycantransglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
   
 0.672
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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