Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tatDDeoxyribonuclease, TatD family; Identified by match to PFAM protein family HMMPF01026 InterPro: Uncharacterized protein family UPF0006; Family membership. (273 aa)    
Predicted Functional Partners:
mltG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
    
 0.900
ABO_1078
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF02646 InterPro: DUF195 shows 46 38dentitie to a rumC family protein. This family contains several bacterial RmuC DNA recombination proteins. The function of the RMUC protein is unknown but it is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures.
       0.838
dsbD-2
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.755
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
    
 0.689
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by sequencesimilarity; putative InterPro: Acyl transferase domain; High confidence in function and specificity.
      0.642
pilZ
Type IV pilus biogenesis protein, identified by sequence similarity to Pseudomonas syringae pv. tomato str. DC3000; High confidence in function and specificity.
  
    0.581
fabF
3-oxoacyl-[acyl-carrier-protein] synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
      0.577
holB
DNA polymerase III, delta prime subunit; High confidence in function and specificity.
  
  
 0.541
nudH
(di)nucleoside polyphosphate hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
      0.541
pabC
4-amino-4-deoxychorismate lyase; Identified by sequence similarity; putative InterPro: Aminotransferases class-IV; High confidence in function and specificity.
  
    0.489
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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