STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)    
Predicted Functional Partners:
ABO_1140
(N-succinyldiaminopimelate aminotransferase, putative) identified by match to TIGR protein family HMMTIGR01140; putative InterPro: Aminotransferases class-I; High confidence in function and specificity.
 
  
 0.952
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.951
argD
Acetylornithine aminotransferase; Identified by sequence similarity; putative InterPro: Aminotransferase class-III pyridoxal-phosphate; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.925
dapD
Tetrahydrodipicolinate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
     
 0.772
rrmA
rRNA large subunit methyltransferase A putative identified by match to PFAM protein family HMMPF01209 InterPro: SAM (and some other nucleotide) binding motif; High confidence in function and specificity.
  
    0.568
ABO_1139
Conserved hypothetical protein ArsC related, Pfam: ArsC family, arsC_related: conserved hypothetical protein; Belongs to the ArsC family.
  
  
 0.564
yfcB
Site-specific DNA-methyltransferase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
 
    0.562
argG
Argininosuccinate synthase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00764 InterPro: Argininosuccinate synthase; High confidence in function and specificity; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.532
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
 
 0.510
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
  
 
 0.503
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (30%) [HD]