Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (386 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 0.972
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
  
   
 0.634
pdxA
Pyridoxal phosphate biosynthetic protein PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
 
   
 0.592
gap-2
Identified by sequence similarity; InterPro: Glyceraldehyde 3-phosphate dehydrogenase; High confidence in function and specificity; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
    
 0.580
hrpA
ATP-dependent helicase HrpA; Identified by sequence similarity; putative InterPro: DEAD/DEAH box helicase; Family membership.
    
 
 0.563
ABO_1176
(conserved hypothetical protein TIGR00051) identified by match to PFAM protein family HMMPF03061 InterPro: 4-hydroxybenzoyl-CoA thioesterase family active site.
       0.551
sdhD
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
   
 0.518
ABO_1175
Alcohol dehydrogenase, iron-containing, putative; (alcohol dehydrogenase iron-containing) identified by match to PFAM protein family HMMPF00465 InterPro: Iron-containing alcohol dehydrogenase; High confidence in function and specificity.
   
   0.475
ABO_1197
Carboxylic ester hydrolases identified by sequencesimilarity; putative InterPro: Alpha/beta hydrolase fold; Family membership.
     
 0.460
estC
InterPro: Carboxylesterases type-B; High confidence in function and specificity.
      
 0.459
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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