STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
nfuAyhgI conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (198 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Identified by sequence similarity; putative identified by match to PFAM potein family HMMPF00266; putative InterPro: Aminotransferase class-V; High confidence in function and specificity.
  
 0.962
sdhB
(succinate dehydrogenase iron-sulfur protein) identified by match to TIGR protein family HMMTIGR00384 InterPro: Succinate dehydrogenase/fumarate reductase iron-sulfur protein catalytic activity: succinate + ubiquinone = fumarate + ubiquinol; High confidence in function and specificity.
  
 0.899
ABO_0670
Oxidoreductase (acting on iron-sulfur proteins as donors with NAD+ or NADP+ as acceptor) identified by sequence similarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership.
  
 0.884
ABO_1717
Flavodoxin reductases (ferredoxin-NADPH reductase)putative; (oxidoreductase FAD-binding putative) identified by sequencesimilarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership.
  
 0.884
ABO_2315
Oxidoreductase iron-sulfur-binding identified by match to PFAM protein family HMMPF00970; Family membership.
  
 0.871
djlA
dnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
  
 
 0.838
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 0.821
ydhD
Glutaredoxin-related protein; conserved hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 0.792
fdx
Ferredoxin, 2Fe-2S; Identified by sequencesimilarity; putative InterPro: Ferredoxin; Family membership.
  
 0.781
yadR
HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
  
 
 0.730
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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