Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhaE2-hydroxy-3-oxopropionate reductase; Identified by sequence similarity; putative; Family membership. (308 aa)    
Predicted Functional Partners:
hyi
Hydroxypyruvate isomerase; Identified by sequencesimilarity; putative; High confidence in function and specificity; Belongs to the hyi family.
 
 0.991
hprA
Glycerate dehydrogenase; Identified by sequencesimilarity; putative; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.908
djlA
dnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
       0.776
fda
Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
  
 0.734
fadC
enoyl-CoA hydratase; Identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
  
 0.595
ABO_1235
Conserved hypothetical protein.
       0.410
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.