STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hyiHydroxypyruvate isomerase; Identified by sequencesimilarity; putative; High confidence in function and specificity; Belongs to the hyi family. (262 aa)    
Predicted Functional Partners:
yhaE
2-hydroxy-3-oxopropionate reductase; Identified by sequence similarity; putative; Family membership.
 
 0.991
hprA
Glycerate dehydrogenase; Identified by sequencesimilarity; putative; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.905
djlA
dnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
       0.781
aldh1
Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.
      
 0.533
mmsB-2
3-hydroxyisobutyrate dehydrogenase; Identified by sequencesimilarity; putative; Family membership.
  
 0.502
ABO_1235
Conserved hypothetical protein.
       0.410
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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