Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
djlAdnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. (280 aa)    
Predicted Functional Partners:
nfuA
yhgI conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.838
dnaK
Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.832
hyi
Hydroxypyruvate isomerase; Identified by sequencesimilarity; putative; High confidence in function and specificity; Belongs to the hyi family.
       0.781
yhaE
2-hydroxy-3-oxopropionate reductase; Identified by sequence similarity; putative; Family membership.
       0.776
iscS
Cysteine desulfurase; Identified by sequence similarity; putative identified by match to PFAM potein family HMMPF00266; putative InterPro: Aminotransferase class-V; High confidence in function and specificity.
  
 0.759
ABO_2084
Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70.
  
 0.736
ABO_2043
Nucleotidyltransferase family protein; Identified by sequencesimilarity; putative InterPro: ADP-glucose pyrophosphorylase; Family membership.
 
    0.735
ABO_2044
Conserved hypothetical protein.
 
    0.656
yadR
HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
  
 
 0.521
iscA
Iron-binding protein IscA; Identified by sequence similarity; putative InterPro: Hypothetical hesB/yadR/yfhF family; Family membership; Belongs to the HesB/IscA family.
  
 
 0.521
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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