Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_1241Transcriptional regulator, putative InterPro: Bacterial regulatory proteins MerR family; Hypothetical protein. (132 aa)    
Predicted Functional Partners:
ivd
isovaleryl-CoA dehydrogenase; Identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity.
  
    0.843
ABO_1239
(Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta), putative) identified by sequencesimilarity; putative InterPro: Carboxyl transferase family; High confidence in function and specificity.
  
  
 0.645
ABO_1243
Sensor histidine kinase containing HisKA, HATPase_c and Response_reg domains, identified by match to PFAM protein family HMMPF04171 InterPro: Histidine kinase C-terminal; conserved hypothetical protein.
   
 
 0.545
ABO_1242
(membrane protein, putative) identified by sequence similarity; putative InterPro: HMGCR/Patched 5TM box; Function unclear.
       0.544
ABO_1238
enoyl-CoA hydratase/isomerase, putative; Identified by match to PFAM protein family HMMPF00378, putative InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
  
    0.543
accC,
acetyl-CoA carboxylase, biotin carboxylase; Identified by match to TIGR protein family HMMTIGR00514 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity.
  
 
 0.526
cbpA
curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity.
  
 
 0.485
acsA-2
acetoacetyl-CoA synthetase; Identified by sequencesimilarity; putative InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity.
 
  
 0.472
ABO_1244
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF01118.
       0.471
ABO_1307
Sensor histidine kinase/respose regulator, contains HisKA, HATPase_c and two Response_reg receiver domains; identified by sequencesimilarity; putative InterPro: Histidine kinase C-terminal; Family membership.
   
 
 0.457
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.