STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
menGS-adenosylmethionine:2-demethylmenaquinonemethyl transferase; Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity). (160 aa)    
Predicted Functional Partners:
ABO_1243
Sensor histidine kinase containing HisKA, HATPase_c and Response_reg domains, identified by match to PFAM protein family HMMPF04171 InterPro: Histidine kinase C-terminal; conserved hypothetical protein.
  
    0.696
ABO_1244
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF01118.
       0.694
ABO_1246
(CBS domain protein, putative) identified by sequence similarity; putative InterPro: CBS domain; Function unclear.
       0.535
ABO_1247
Cell division protein FtsK; (ftsK) identified by sequence similarity; putative; Hypothetical protein.
       0.433
ABO_1242
(membrane protein, putative) identified by sequence similarity; putative InterPro: HMGCR/Patched 5TM box; Function unclear.
       0.407
fumA
Fumarate hydratase, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.400
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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