STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (364 aa)    
Predicted Functional Partners:
hflD
Conserved hypothetical protein; Identified by sequence similarity.
  
  
 0.961
purB
Adenylosuccinate lyase; purB identified by sequencesimilarity; putative InterPro: Adenylosuccinate lyase; High confidence in function and specificity; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
  
 0.902
trmU-2
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Identified by sequencesimilarity; High confidence in function and specificity.
     
  0.900
trmE
tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 0.846
nudJ
MutT/NUDIX family protein; Region start changed from 1451926 to 1451869 (-57 bases); Belongs to the Nudix hydrolase family. NudJ subfamily.
  
    0.816
gidA
Glucose-inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
 
 0.812
moaE
Molybdenum cofactor biosynthesis protein E; Identified by sequencesimilarity; putative InterPro: Molydopterin converting factor subunit 2; High confidence in function and specificity.
     
 0.675
ABO_1272
Conserved hypothetical protein; Identified by Glimmer2; putative.
     
 0.659
ABO_1271
Acetyltransferase (transferring groups other than amino-acyl groups) identified by match to PFAM protein family HMMPF00583 InterPro: GCN5-related N-acetyltransferase; Family membership.
 
     0.628
moaD
Molybdenum cofactor biosynthesis protein D; Identified by sequence similarity; High confidence in function and specificity.
     
 0.620
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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