STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icd-2(isocitrate dehydrogenase NADP-dependent monomeric-type) identified by match to PFAM protein family HMMPF03971 InterPro: Isocitrate dehydrogenase NADP-dependent monomeric type; High confidence in function and specificity; Belongs to the monomeric-type IDH family. (740 aa)    
Predicted Functional Partners:
icdA
(icd) (isocitrate dehydrogenase NADP-dependentprokaryotic-type) identified by match to TIGR protein family HMMTIGR00183 InterPro: Isocitrate dehydrogenase NADP-dependent prok type; High confidence in function and specificity.
    
 0.957
acnB
Aconitate hydratase 2; Identified by sequence similarity; putative InterPro: Aconitate hydratase 2; High confidence in function and specificity; Belongs to the aconitase/IPM isomerase family.
  
 
 0.932
sucA
(kgdA) (2-oxoglutarate dehydrogenase E1 component) identified by sequence similarity; putative InterPro: Dehydrogenase E1 component; High confidence in function and specificity.
   
 
 0.920
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 
 0.917
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.910
icd
(isocitrate dehydrogenase NADP-dependent, oxalosuccinate decarboxylase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00180 and TIGRFAM protein family HMMTIGR00175 InterPro: Isocitrate and isopropylmalate dehydrogenases; High confidence in function and specificity.
     
 0.901
gltB
Glutamate synthase, large subunit; Identified by sequencesimilarity; putative identified by match to PFAM protein family HMMPF04897 and HMMPF01645 InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity.
     
 0.893
ABO_1810
Ferredoxin, 4Fe-4S; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
  
 0.844
purB
Adenylosuccinate lyase; purB identified by sequencesimilarity; putative InterPro: Adenylosuccinate lyase; High confidence in function and specificity; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.843
gdhA-2
(glutamate dehydrogenase, NAD(P)-specific glutamate dehydrogenase) identified by sequence similarity; putative identified by match to PFAM protein families HMMPF02812 and HMMPF00208 InterPro: Glutamate/leucine/phenylalanine/valine dehydrogenase; High confidence in function and specificity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.820
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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