node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dhbP | pgsA | ABO_2172 | ABO_1306 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.422 |
dhbP | rec2 | ABO_2172 | ABO_1052 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | (DNA internalization-related competence protein ComEC/Rec2) identified by match to PFAM protein family HMMPF03772 InterPro: DNA internalization-related competence protein ComEC/Rec2 Possibly exported; Family membership. | 0.648 |
dhbP | uvrA | ABO_2172 | ABO_0427 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.529 |
dhbP | uvrC | ABO_2172 | ABO_1305 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.602 |
gacA | pgsA | ABO_1304 | ABO_1306 | DNA-binding response regulator GacA; Identified by sequence similarity; putative InterPro: Response regulator receiver domain; Specificity unclear. | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.429 |
gacA | uvrC | ABO_1304 | ABO_1305 | DNA-binding response regulator GacA; Identified by sequence similarity; putative InterPro: Response regulator receiver domain; Specificity unclear. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.757 |
mutM | polA | ABO_2583 | ABO_2659 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.979 |
mutM | uvrC | ABO_2583 | ABO_1305 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.615 |
pgsA | dhbP | ABO_1306 | ABO_2172 | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.422 |
pgsA | gacA | ABO_1306 | ABO_1304 | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | DNA-binding response regulator GacA; Identified by sequence similarity; putative InterPro: Response regulator receiver domain; Specificity unclear. | 0.429 |
pgsA | rec2 | ABO_1306 | ABO_1052 | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | (DNA internalization-related competence protein ComEC/Rec2) identified by match to PFAM protein family HMMPF03772 InterPro: DNA internalization-related competence protein ComEC/Rec2 Possibly exported; Family membership. | 0.423 |
pgsA | uvrC | ABO_1306 | ABO_1305 | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.678 |
polA | mutM | ABO_2659 | ABO_2583 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.979 |
polA | rep | ABO_2659 | ABO_2538 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. | 0.572 |
polA | uvrA | ABO_2659 | ABO_0427 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.643 |
polA | uvrB | ABO_2659 | ABO_0945 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.691 |
polA | uvrC | ABO_2659 | ABO_1305 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.611 |
polA | uvrD | ABO_2659 | ABO_2690 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA helicase II; Identified by match to PFAM protein family HMMPF03711 InterPro: UvrD/REP helicase; High confidence in function and specificity. | 0.572 |
rec2 | dhbP | ABO_1052 | ABO_2172 | (DNA internalization-related competence protein ComEC/Rec2) identified by match to PFAM protein family HMMPF03772 InterPro: DNA internalization-related competence protein ComEC/Rec2 Possibly exported; Family membership. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.648 |
rec2 | pgsA | ABO_1052 | ABO_1306 | (DNA internalization-related competence protein ComEC/Rec2) identified by match to PFAM protein family HMMPF03772 InterPro: DNA internalization-related competence protein ComEC/Rec2 Possibly exported; Family membership. | (CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase) identified by sequencesimilarity; putative InterPro: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.423 |