STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pntBPyridine nucleotide transhydrogenase, B subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (461 aa)    
Predicted Functional Partners:
ABO_1328
Oxidoreductase; Ocidoredutase (acting on NADH or NADPH with NAD+ or NADP+ as acceptor); Family membership.
 0.999
pntA
Pyridine nucleotide transhydrogenase A subunit; (transcriptional regulator LysR family) identified by match to PFAM protein family HMMPF03466 InterPro: Alanine dehydrogenase and pyridine nucleotide transhydrogenase; High confidence in function and specificity.
 0.999
nadE
NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.920
sth
(soluble pyridine nucleotide transhydrogenase) identified by sequence similarity; putative InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity.
     
 0.908
yfjB
Nicotinamide adenine dinucleotide kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.905
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.902
ABO_1622
(MazG nucleotide pyrophosphohydrolase domain family protein) identified by match to TIGR protein family HMMTIGR00444 InterPro: MazG family protein; Function unclear.
    
  0.901
cobB
Identified by match to PFAM protein family HMMPF02146 InterPro: Sir2 family; High confidence in function and specificity; Belongs to the sirtuin family. Class III subfamily.
    
  0.900
ABO_1228
NADH pyrophosphatase, putative; Identified by sequence similarity; putative InterPro: NUDIX hydrolase; Specificity unclear.
     
  0.900
ABO_1330
ABC1/ AarF family protein; Region start changed from 1511994 to 1511937 (-57 bases).
       0.464
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.