STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemFCoproporphyrinogen oxidase; Identified by match to TIGR protein family HMMTIGR00538 InterPro: Oxygen-independent coproporphyrinogen III oxidase HemN; High confidence in function and specificity; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (457 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.961
hemF-2
Coproporphyrinogen III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.950
ABO_0357
Conserved hypothetical protein.
    
 0.914
ABO_1347
Iron-sulfur cluster-binding protein; Identified by match to PFAM protein family HMMPF00037 InterPro: 4Fe-4S ferredoxin iron-sulfur binding domain; High confidence in function and specificity.
 
  
 0.898
ccoN-1
Identified by match to TIGR protein family HMMTIGR00780 InterPro: Cytochrome c oxidase cbb3-type subunit I; High confidence in function and specificity; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.883
ccoO-1
Cytochrome c oxidase, cbb3-type, subunit II; Identified by match to TIGR protein family HMMTIGR00781 InterPro: Cytochrome C oxidase mono-heme subunit/FixO; Family membership.
 
  
 0.860
anr
Transcriptional regulator Anr; Identified by sequencesimilarity; putative InterPro: Cyclic nucleotide-binding domain; Specificity unclear.
 
  
 0.850
ABO_1922
Outer membrane protein W precursor., OmpW family; Specificity unclear.
 
  
 0.819
ABO_1343
Conserved hypothetical protein.
 
   
 0.769
ABO_1348
Cytochrome c oxidase, cbb3-type, subunit III, putative; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
  
 0.754
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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