STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tnpA(Transposon protein A, transposition regulatory protein tnpA homolog - Sphingomonas aromaticivorans plasmid pNL1, putative) InterPro: Phage integrase; High confidence in function and specificity; Belongs to the 'phage' integrase family. (400 aa)    
Predicted Functional Partners:
tnpB
Transposon protein B, putative; (transponson protein B homolog - Sphingomonas aromaticivorans plasmid pNL1) InterPro: Phage integrase; Family membership.
 
     0.946
xerC
Integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
 
 
 0.777
xerD
Integrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
  
     0.720
topA
Type I DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...]
 
  
 0.474
ABO_1353
Transcriptional regulator, LysR family; Identified by sequencesimilarity; putative InterPro: Bacterial regulatory protein LysR family; Family membership; Belongs to the LysR transcriptional regulatory family.
     
 0.471
ABO_2221
Conserved hypothetical protein; (competence protein ComF putative) identified by sequence similarity; putative.
   
    0.470
ABO_2155
(two-component protein: Na-solute symporter/sensory box histidinekinase/response regulator putative) identified by match to PFAM protein family HMMPF02518 and HMMPF00072; putative InterPro: Sodium:solute symporter family TMHMM: reportin 12 transmembrane helices; Family membership.
  
  
 0.402
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.