Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ABO_1435(para-aminobenzoate synthase component I, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00425 and match to TIGRFAM protein family HMMTIGR00553 InterPro: Anthranilate synthase component I and chorismate binding enzyme; Function unclear. (378 aa)    
Predicted Functional Partners:
trpG
(anthranilate synthase component II, glutamine amidotransferase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00117 and TIGRFAM protein family HMMTIGR00566; putative; High confidence in function and specificity.
 0.999
trpC
Indole-3-glycerol phosphate synthase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00218 InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family.
 
 0.980
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.972
pabC
4-amino-4-deoxychorismate lyase; Identified by sequence similarity; putative InterPro: Aminotransferases class-IV; High confidence in function and specificity.
 
 
 0.947
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.935
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.921
trpF
N-(5'-phosphoribosyl)anthranilate isomerase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00697 InterPro: N-(5phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity; Belongs to the TrpF family.
 
  
 0.910
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.907
pheA
(P-protein including chorismate mutase and prephenate dehydratase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01817 InterPro: Prephenate dehydratase (PDT); High confidence in function and specificity.
  
 
 0.907
ABO_1296
Glycosyl transferase, putative; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF02885; putative InterPro: Glycosyl transferase family; Family membership.
 
 
 0.858
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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