STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_14385'-nucleotidase; 5-nucleotidase putative identified by sequencesimilarity; putative; conserved hypothetical protein. (306 aa)    
Predicted Functional Partners:
cpdA
Icc protein, putative; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
    
  0.901
pyrR
Transcriptional regulator PyrR; Identified by sequence similarity; putative; High confidence in function and specificity.
     
  0.900
guaA
(glutamine amidotransferase class I) identified by match to TIGR protein family HMMTIGR00888; Family membership.
     
  0.900
gmk-2
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
  0.900
dut
Deoxyuridine 5-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
     
  0.900
ABO_0278
Identified by match to PFAM protein family HMMPF00702 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership.
     
  0.900
ABO_0477
Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
maf-1
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     
  0.900
nadC
(nicotinate-nucleotide pyrophosphorylase) identified by sequencesimilarity; putative InterPro: Nicotinate-nucleotide pyrophosphorylase; High confidence in function and specificity; Belongs to the NadC/ModD family.
     
  0.900
ABO_0657
(decarboxylase family protein) identified by sequencesimilarity; putative; Family membership.
     
  0.900
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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