node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO_1296 | rsmC | ABO_1296 | ABO_1448 | Glycosyl transferase, putative; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF02885; putative InterPro: Glycosyl transferase family; Family membership. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.551 |
hepA | rsmC | ABO_1894 | ABO_1448 | RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.451 |
hfq | rho | ABO_2203 | ABO_2463 | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | 0.658 |
hfq | rsmC | ABO_2203 | ABO_1448 | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.459 |
hfq | rsmH | ABO_2203 | ABO_0590 | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.559 |
hfq | rsmI | ABO_2203 | ABO_0587 | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Tetrapyrrole methylase family protein, putative; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.580 |
hfq | sun; | ABO_2203 | ABO_0129 | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | tRNA and rRNA cytosine-C5-methylase, putative; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.554 |
hrpB | rsmC | ABO_1449 | ABO_1448 | HrpB protein; Identified by sequencesimilarity; putative InterPro: DEAD/DEAH box helicase; High confidence in function and specificity. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.558 |
obg | rsmC | ABO_0454 | ABO_1448 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.467 |
obg | rsmH | ABO_0454 | ABO_0590 | GTP-binding protein, GTP1/Obg family; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.554 |
rho | hfq | ABO_2463 | ABO_2203 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.658 |
rho | rsmC | ABO_2463 | ABO_1448 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.424 |
rho | rsmH | ABO_2463 | ABO_0590 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.524 |
rho | rsmI | ABO_2463 | ABO_0587 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | Tetrapyrrole methylase family protein, putative; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.490 |
rho | sun; | ABO_2463 | ABO_0129 | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. | tRNA and rRNA cytosine-C5-methylase, putative; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.461 |
rlmL | rsmC | ABO_1005 | ABO_1448 | Conserved hypothetical protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.421 |
rsmC | ABO_1296 | ABO_1448 | ABO_1296 | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Glycosyl transferase, putative; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF02885; putative InterPro: Glycosyl transferase family; Family membership. | 0.551 |
rsmC | hepA | ABO_1448 | ABO_1894 | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | 0.451 |
rsmC | hfq | ABO_1448 | ABO_2203 | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.459 |
rsmC | hrpB | ABO_1448 | ABO_1449 | Ribosomal ribonucleate guanine-2-methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | HrpB protein; Identified by sequencesimilarity; putative InterPro: DEAD/DEAH box helicase; High confidence in function and specificity. | 0.558 |