STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00697 InterPro: N-(5phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity; Belongs to the TrpF family. (218 aa)    
Predicted Functional Partners:
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.999
trpC
Indole-3-glycerol phosphate synthase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00218 InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family.
 
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.996
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.994
trpG
(anthranilate synthase component II, glutamine amidotransferase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00117 and TIGRFAM protein family HMMTIGR00566; putative; High confidence in function and specificity.
  
 0.994
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
 
  
 0.925
ABO_1435
(para-aminobenzoate synthase component I, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00425 and match to TIGRFAM protein family HMMTIGR00553 InterPro: Anthranilate synthase component I and chorismate binding enzyme; Function unclear.
 
  
 0.910
ABO_1296
Glycosyl transferase, putative; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF02885; putative InterPro: Glycosyl transferase family; Family membership.
 
  
 0.834
truA
Pseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
     
 0.777
pheA
(P-protein including chorismate mutase and prephenate dehydratase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01817 InterPro: Prephenate dehydratase (PDT); High confidence in function and specificity.
 
  
 0.762
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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