| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceA | aceF | ABO_2741 | ABO_0623 | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.819 |
| aceA | prpB | ABO_2741 | ABO_1433 | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.918 |
| aceA | sdhA | ABO_2741 | ABO_1498 | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | (succinate dehydrogenase flavoprotein subunit) identified by sequence similarity; putative InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein catalytic activity: succinate + acceptor = fumarate + reduced acceptor; High confidence in function and specificity; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.609 |
| aceA | sucC | ABO_2741 | ABO_1493 | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.924 |
| aceA | sucD | ABO_2741 | ABO_1492 | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.918 |
| aceF | aceA | ABO_0623 | ABO_2741 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | 0.819 |
| aceF | prpB | ABO_0623 | ABO_1433 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.808 |
| aceF | sdhA | ABO_0623 | ABO_1498 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | (succinate dehydrogenase flavoprotein subunit) identified by sequence similarity; putative InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein catalytic activity: succinate + acceptor = fumarate + reduced acceptor; High confidence in function and specificity; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.554 |
| aceF | sdhB | ABO_0623 | ABO_1497 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | (succinate dehydrogenase iron-sulfur protein) identified by match to TIGR protein family HMMTIGR00384 InterPro: Succinate dehydrogenase/fumarate reductase iron-sulfur protein catalytic activity: succinate + ubiquinone = fumarate + ubiquinol; High confidence in function and specificity. | 0.676 |
| aceF | sdhC | ABO_0623 | ABO_1500 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, cytochrome b556 subunit; Identified by sequence similarity; putative part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein; High confidence in function and specificity. | 0.479 |
| aceF | sdhD | ABO_0623 | ABO_1499 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.424 |
| aceF | sucA | ABO_0623 | ABO_1496 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | (kgdA) (2-oxoglutarate dehydrogenase E1 component) identified by sequence similarity; putative InterPro: Dehydrogenase E1 component; High confidence in function and specificity. | 0.993 |
| aceF | sucB | ABO_0623 | ABO_1495 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.502 |
| aceF | sucC | ABO_0623 | ABO_1493 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.964 |
| aceF | sucD | ABO_0623 | ABO_1492 | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.947 |
| prpB | aceA | ABO_1433 | ABO_2741 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | 0.918 |
| prpB | aceF | ABO_1433 | ABO_0623 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.808 |
| prpB | sucC | ABO_1433 | ABO_1493 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.912 |
| prpB | sucD | ABO_1433 | ABO_1492 | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.920 |
| sdhA | aceA | ABO_1498 | ABO_2741 | (succinate dehydrogenase flavoprotein subunit) identified by sequence similarity; putative InterPro: Fumarate reductase/succinate dehydrogenase flavoprotein N-terminal part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and an hydrophobic anchor protein catalytic activity: succinate + acceptor = fumarate + reduced acceptor; High confidence in function and specificity; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity. | 0.609 |
