Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ABO_1601Aldolase, putative; Deleted EC_number 4.1.2.1; (aldolase, putative) identified by match to TIGR protein family HMMTIGR01086, putative InterPro: Class II Aldolase and Adducin N-terminal domain; Family membership. (261 aa)    
Predicted Functional Partners:
ABO_1602
(phosphohydrolase, HD domain protein family, putative) identified by match to PFAM protein family HMMPF03466; Family membership.
 
     0.861
anr-2
Transcriptional regulator Anr; Identified by sequencesimilarity; putative InterPro: Cyclic nucleotide-binding domain; Family membership.
       0.613
ABO_1324
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.470
mtnD
ARD/ARD' family protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
  
 0.445
ABO_1407
Sugar kinase, putative; (sugar kinase) identified by sequence similarity; putative InterPro: Carbohydrate kinase FGGY family; Family membership.
  
  
 0.419
ABO_0424
Conserved hypothetical protein.
  
     0.415
ABO_1603
Conserved hypothetical protein.
       0.408
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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