Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fadCenoyl-CoA hydratase; Identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity. (371 aa)    
Predicted Functional Partners:
mmsB
3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; High confidence in function and specificity.
  
 0.985
mvaB
hydroxymethylglutaryl-CoA lyase; Identified by sequence similarity; putative InterPro: HMG-CoA Lyase-like family; High confidence in function and specificity; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.841
acdA
acyl-CoA dehydrogenase; Identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; Family membership.
 
 0.781
fadA3
3-ketoacyl-CoA thiolase; Identified by match to PFAM protein family HMMPF00108 InterPro: thiolase family protein; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.716
ech1
(enoyl-CoA hydratase/isomerase family protein, putative) identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
    0.713
fadAx
acetyl-CoA C-acetyltransferase; (3-ketoacyl-CoA thiolase) identified by sequencesimilarity; putative InterPro: Thiolase; Specificity unclear; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.676
fadA1
acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.625
pcaF
(beta-ketoadipyl CoA thiolase PcaF) identified by match to PFAM protein family HMMPF00108 InterPro: Thiolase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.625
fadA
(Acetyl CoA acetyltransferase) identified by sequence similarity; putative InterPro: Thiolase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.625
fadA2
3-oxoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
  
 0.625
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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