| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABO_1665 | ABO_1666 | ABO_1665 | ABO_1666 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | Superfamily I DNA and RNA helicases domain protein. | 0.773 |
| ABO_1665 | ABO_1904 | ABO_1665 | ABO_1904 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | (Sco1/SenC family protein) identified by match to PFAM protein family HMMPF00578. | 0.444 |
| ABO_1665 | dnaN | ABO_1665 | ABO_0002 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.534 |
| ABO_1665 | ligA1 | ABO_1665 | ABO_0949 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.499 |
| ABO_1665 | mutL | ABO_1665 | ABO_2205 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.474 |
| ABO_1665 | polA | ABO_1665 | ABO_2659 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.575 |
| ABO_1665 | recA | ABO_1665 | ABO_1801 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.545 |
| ABO_1665 | recQ | ABO_1665 | ABO_1161 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | ATP-dependent DNA helicase RecQ; High confidence in function and specificity. | 0.460 |
| ABO_1665 | recQ1 | ABO_1665 | ABO_0735 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | ATP-dependent DNA helicase RecQ; Identified by sequencesimilarity; putative InterPro: ATP-dependent DNA helicase RecQ; High confidence in function and specificity. | 0.460 |
| ABO_1665 | topA | ABO_1665 | ABO_1012 | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | Type I DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...] | 0.586 |
| ABO_1666 | ABO_1665 | ABO_1666 | ABO_1665 | Superfamily I DNA and RNA helicases domain protein. | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | 0.773 |
| ABO_1904 | ABO_1665 | ABO_1904 | ABO_1665 | (Sco1/SenC family protein) identified by match to PFAM protein family HMMPF00578. | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | 0.444 |
| dnaN | ABO_1665 | ABO_0002 | ABO_1665 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | 0.534 |
| dnaN | mutL | ABO_0002 | ABO_2205 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.939 |
| dnaN | polA | ABO_0002 | ABO_2659 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
| dnaN | recA | ABO_0002 | ABO_1801 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.905 |
| dnaN | recQ | ABO_0002 | ABO_1161 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ; High confidence in function and specificity. | 0.600 |
| dnaN | recQ1 | ABO_0002 | ABO_0735 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecQ; Identified by sequencesimilarity; putative InterPro: ATP-dependent DNA helicase RecQ; High confidence in function and specificity. | 0.600 |
| dnaN | topA | ABO_0002 | ABO_1012 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Type I DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...] | 0.639 |
| ligA1 | ABO_1665 | ABO_0949 | ABO_1665 | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | Hypothetical protein; (helicase putative) identified by match to PFAM protein family HMMPF00580; Hypothetical protein. | 0.499 |
