Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pfeS(sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity. (451 aa)    
Predicted Functional Partners:
pfeR
DNA-binding response regulator; Identified by match to PFAM protein family HMMPF00072; Specificity unclear.
 
 0.997
ABO_1709
DNA-binding response regulator) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Function unclear.
 
 
 0.839
rstA
DNA-binding response regulator; Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.838
colR
(DNA-binding heavy metal response regulator, putative) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear.
 
 
 0.837
phoP
DNA-binding heavy metal response regulator, putative; Identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear.
 
 
 0.831
pilH-2
(PilH; regulatory protein pilH family) identified by sequence similarity; putative InterPro: Response regulator receiver domain; Family membership.
 
 
 0.829
ABO_2001
(Transcriptional regulatory protein, putative) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Family membership.
 
 
 0.827
phoP-2
DNA-binding heavy metal response regulator, putative; Identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear.
 
 
 0.823
ompR1
(ompR-1) identified by sequencesimilarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.821
ygiX
Transcriptional regulatory protein qseb; Probable 2-component transcription regulator identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.820
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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