Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_1717Flavodoxin reductases (ferredoxin-NADPH reductase)putative; (oxidoreductase FAD-binding putative) identified by sequencesimilarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership. (373 aa)    
Predicted Functional Partners:
ABO_1716
Conserved hypothetical protein.
 
 0.999
ABO_2585
(fatty acid desaturase family protein, putative) identified by match to PFAM protein family HMMPF00487 InterPro: Fatty acid desaturase; High confidence in function and specificity.
     
 0.908
nfuA
yhgI conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.884
ABO_1718
Transcriptional regulator TetR family identified by match to PFAM protein family HMMPF00440 InterPro: Bacterial regulatory proteins TetR family; Family membership.
 
  
 0.849
iscS
Cysteine desulfurase; Identified by sequence similarity; putative identified by match to PFAM potein family HMMPF00266; putative InterPro: Aminotransferase class-V; High confidence in function and specificity.
  
 0.660
fadH
(2,4-dienoyl-CoA reductase FadH) identified by sequencesimilarity; putative InterPro: NADH:flavin oxidoreductase/NADH oxidase; High confidence in function and specificity.
  
 0.656
ABO_1590
Conserved hypothetical protein.
 
  
 0.636
ABO_2315
Oxidoreductase iron-sulfur-binding identified by match to PFAM protein family HMMPF00970; Family membership.
 
  
 0.635
alkB1
Alkane 1-monooxygenase; Catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C5-C12 hydrocarbons. Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
 
  
 0.599
alkB2
Alkane-1-monooxygenase; Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C8-C16 hydrocarbons; Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
 
  
 0.597
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (24%) [HD]