| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acsA | acsA-3 | ABO_0334 | ABO_1731 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | 0.912 |
| acsA | adhA | ABO_0334 | ABO_1231 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | (alcohol dehydrogenase, putative) identified by sequencesimilarity; putative InterPro: Zinc-containing alcohol dehydrogenase superfamily; Family membership. | 0.906 |
| acsA | aldh1 | ABO_0334 | ABO_0962 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.912 |
| acsA | alkH | ABO_0334 | ABO_2709 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.912 |
| acsA | fadA1 | ABO_0334 | ABO_0253 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. | 0.914 |
| acsA | fadA2 | ABO_0334 | ABO_1653 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-oxoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.829 |
| acsA | fadA3 | ABO_0334 | ABO_2452 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-ketoacyl-CoA thiolase; Identified by match to PFAM protein family HMMPF00108 InterPro: thiolase family protein; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. | 0.829 |
| acsA | mmsA | ABO_0334 | ABO_0020 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | (methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity. | 0.912 |
| acsA | mmsB | ABO_0334 | ABO_0022 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; High confidence in function and specificity. | 0.823 |
| acsA | prpC | ABO_0334 | ABO_1432 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Methylcitrate synthase putative identified by sequence similarity; putative InterPro: Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.926 |
| acsA-3 | acsA | ABO_1731 | ABO_0334 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.912 |
| acsA-3 | adhA | ABO_1731 | ABO_1231 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | (alcohol dehydrogenase, putative) identified by sequencesimilarity; putative InterPro: Zinc-containing alcohol dehydrogenase superfamily; Family membership. | 0.906 |
| acsA-3 | aldh1 | ABO_1731 | ABO_0962 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear. | 0.825 |
| acsA-3 | alkH | ABO_1731 | ABO_2709 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | (aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity. | 0.825 |
| acsA-3 | fadA1 | ABO_1731 | ABO_0253 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. | 0.829 |
| acsA-3 | fadA2 | ABO_1731 | ABO_1653 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | 3-oxoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.829 |
| acsA-3 | fadA3 | ABO_1731 | ABO_2452 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | 3-ketoacyl-CoA thiolase; Identified by match to PFAM protein family HMMPF00108 InterPro: thiolase family protein; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family. | 0.829 |
| acsA-3 | mmsA | ABO_1731 | ABO_0020 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | (methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity. | 0.912 |
| acsA-3 | mmsB | ABO_1731 | ABO_0022 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | 3-hydroxyisobutyrate dehydrogenase; Identified by sequence similarity; High confidence in function and specificity. | 0.823 |
| acsA-3 | prpC | ABO_1731 | ABO_1432 | (acetyl-CoA synthetase putative) identified by sequence similarity; putative; High confidence in function and specificity. | Methylcitrate synthase putative identified by sequence similarity; putative InterPro: Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family. | 0.926 |
