STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtaDConserved hypothetical protein; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (443 aa)    
Predicted Functional Partners:
deoD
Nucleoside phosphorylase, putative; (heat shock protein putative) identified by sequence similarity; putative InterPro: Purine and other phosphorylases family 2; High confidence in function and specificity.
 
 0.975
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
   
 0.963
ahcy
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.922
dsm
C-5 cytosine-specific DNA methylase family protein; DNA-cytosine methyltransferase identified by sequence similarity; putative InterPro: C-5 cytosine-specific DNA methylase; Specificity unclear.
   
 
  0.903
ABO_0477
Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
ubiG
3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
  
 0.830
gph
Phosphoglycolate phosphatase; Identified by match to PFAM protein family HMMPF00702; putative InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership.
  
    0.780
birA
biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.679
ABO_1755
Oxidoreductase short chaindehydrogenase/reductase family identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Family membership.
       0.583
ABO_0221
Type II/IV secretion system protein family; Family membership.
      
 0.559
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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