Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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pyrC-3Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.986
pyrB
Aspartate carbamoyltransferase; Identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.983
pyrC
(dihydroorotase multifunctional complex type; DHOase) identified by sequencesimilarity; putative InterPro: Dihydroorotase multifunctional complex type; High confidence in function and specificity.
    
 0.922
pyrC-2
Dihydroorotase, multifunctional complex type; Identified by sequencesimilarity; putative InterPro: Dihydroorotase multifunctional complex type; Hypothetical protein.
    
 0.910
ABO_1793
Cobalamin synthesis protein/P47K family protein; CobW/P47K family protein identified by match to PFAM protein family HMMPF02492 InterPro: Cobalamin synthesis protein/P47K; Function unclear.
       0.838
carA
(carbamoyl-phosphate synthase small subunit, carbamoyl-phosphate synthetase glutamine chain) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00988; putative InterPro: Glutamine amidotransferase class-I; High confidence in function and specificity; Belongs to the CarA family.
   
  
 0.755
carB
(carbamoyl-phosphate synthase large subunit, carbamoyl- phosphate synthetase ammonia chain) identified by sequence similarity; putative identified by match to PFAM protein families HMMPF02786 and HMMPF00289 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity.
   
  
 0.717
ABO_1792
Small multidrug resistance protein; Identified by match to PFAM protein family HMMPF00893 InterPro: Integral membrane protein DUF7; Family membership.
       0.682
ABO_1986
Unknown EC_number 21.7.3.11; (two-component sensor histidine kinase protein, putative) identified by match to PFAM protein family HMMPF03596 InterPro: Permeases for cytosine/purines uracil thiamine allantoin; Family membership.
   
   0.654
ABO_1791
(acetyl-CoA hydrolase/transferase family protein) identified by sequencesimilarity; putative; Family membership.
       0.614
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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