Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
lysC(aspartokinase, aspartate kinase monofunctional class) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00696; putative InterPro: Aspartokinase superfamily; High confidence in function and specificity; Belongs to the aspartokinase family. (408 aa)    
Predicted Functional Partners:
asd-2
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.985
asd-1
Aspartate-semialdehyde dehydrogenase; Identified by sequence similarity; putative identified by match to PFAM protein families HMMPF01118 and HMMPF02774 InterPro: Semialdehyde dehydrogenase; High confidence in function and specificity; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.984
hom
Homoserine dehydrogenase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00742 InterPro: Homoserine dehydrogenase; High confidence in function and specificity.
 
 0.983
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.971
argG
Argininosuccinate synthase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00764 InterPro: Argininosuccinate synthase; High confidence in function and specificity; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.887
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.826
aspC
(aspartate aminotransferase, transaminase A) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00155 InterPro: Aminotransferases class-I; High confidence in function and specificity.
  
 
 0.824
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.821
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.808
pyrB
Aspartate carbamoyltransferase; Identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
 0.801
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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