Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
iscSCysteine desulfurase; Identified by sequence similarity; putative identified by match to PFAM potein family HMMPF00266; putative InterPro: Aminotransferase class-V; High confidence in function and specificity. (383 aa)    
Predicted Functional Partners:
rrf2
Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
 
  
 0.997
ABO_0772
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 0.987
tusA
Conserved hypothetical protein; Sulfur carrier protein which probably makes part of a sulfur- relay system; Belongs to the sulfur carrier protein TusA family.
   
 0.987
moeB
Molybdopterin biosynthesis MoeB proteinputative identified by sequencesimilarity; putative InterPro: UBA/THIF-type NAD/FAD binding fold; Family membership.
   
 0.981
ABO_2263
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
   
 0.972
nfuA
yhgI conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 0.962
glpE
Thiosulfate sulfurtransferase; Identified by sequence similarity InterPro: Rhodanese/cdc25 fold; High confidence in function and specificity.
  
 0.929
iscA
Iron-binding protein IscA; Identified by sequence similarity; putative InterPro: Hypothetical hesB/yadR/yfhF family; Family membership; Belongs to the HesB/IscA family.
 
 
 0.925
dnaK
Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.872
yadR
HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 
 0.821
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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