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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbDThiol:disulfide interchange protein DsbD; Identified by match to PFAM protein family HMMPF00085 InterPro: Cytochrome c biogenesis protein transmembrane region; High confidence in function and specificity. (626 aa)    
Predicted Functional Partners:
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 
 0.951
dsbC
Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.918
dsbE
Thiol:disulfide interchange protein DsbE; Identified by sequence similarity; putative InterPro: Periplasmic protein thiol:disulfide oxidoreductase DsbE; High confidence in function and specificity.
  
 
 0.914
ABO_2006
(thioredoxin family protein, putative) identified by sequence similarity; putative InterPro: Thioredoxin; High confidence in function and specificity.
  
 
 0.874
ABO_0032
Conserved hypothetical protein; Identified by sequence similarity. InterPro: Thioredoxin.
  
 
 0.761
ahpF
(alkyl hydroperoxide reductase F subunit) identified by sequence similarity; putative InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity.
      
 0.704
dsbG
Thiol:disulfide interchange protein DsbG; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.675
ABO_2000
Sensor histidine kinase; Identified by match to PFAM protein family HMMPF00512 InterPro: Histidine kinase C-terminal; Family membership.
 
  
 0.661
ABO_0816
Thioredoxin, putative; (trx-1) (thioredoxin) identified by match to PFAM protein family HMMPF00085 InterPro: Thioredoxin; High confidence in function and specificity.
  
 
 0.660
dsbA
Thiol:disulfide interchange protein, DsbA family; Identified by sequencesimilarity; putative InterPro: DSBA oxidoreductase; High confidence in function and specificity.
 
 
 0.654
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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