Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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accBacetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (150 aa)    
Predicted Functional Partners:
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.999
accD-2
acetyl-CoA carboxylase, carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.997
accA-2
acetyl-CoA carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.992
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by sequencesimilarity; putative InterPro: Acyl transferase domain; High confidence in function and specificity.
 
 
 0.968
fabB
Identified by match to PFAM protein family HMMPF02801 InterPro: Beta-ketoacyl synthase; Family membership; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.938
aceF
Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.914
mmsA
(methylmalonate semialdehyde dehydrogenase) identified by sequence similarity; putative InterPro: Aldehyde dehydrogenase family distal valine metabolic pathway; High confidence in function and specificity.
    
  0.904
fadA1
acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.904
fadAx
acetyl-CoA C-acetyltransferase; (3-ketoacyl-CoA thiolase) identified by sequencesimilarity; putative InterPro: Thiolase; Specificity unclear; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.904
fadA
(Acetyl CoA acetyltransferase) identified by sequence similarity; putative InterPro: Thiolase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.904
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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