Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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trpG(anthranilate synthase component II, glutamine amidotransferase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00117 and TIGRFAM protein family HMMTIGR00566; putative; High confidence in function and specificity. (200 aa)    
Predicted Functional Partners:
ABO_1435
(para-aminobenzoate synthase component I, putative) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00425 and match to TIGRFAM protein family HMMTIGR00553 InterPro: Anthranilate synthase component I and chorismate binding enzyme; Function unclear.
 0.999
trpC
Indole-3-glycerol phosphate synthase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00218 InterPro: Indole-3-glycerol phosphate synthase; High confidence in function and specificity; Belongs to the TrpC family.
  
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
trpE
Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...]
 0.999
trpF
N-(5'-phosphoribosyl)anthranilate isomerase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00697 InterPro: N-(5phosphoribosyl)anthranilate isomerase (PRAI); High confidence in function and specificity; Belongs to the TrpF family.
  
 0.994
pheA
(P-protein including chorismate mutase and prephenate dehydratase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01817 InterPro: Prephenate dehydratase (PDT); High confidence in function and specificity.
 
 
 0.969
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
 0.963
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.952
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.929
ABO_1296
Glycosyl transferase, putative; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF02885; putative InterPro: Glycosyl transferase family; Family membership.
 
  
 0.809
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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