Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABO_2043Nucleotidyltransferase family protein; Identified by sequencesimilarity; putative InterPro: ADP-glucose pyrophosphorylase; Family membership. (221 aa)    
Predicted Functional Partners:
ABO_2044
Conserved hypothetical protein.
 
 0.999
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
    
 0.905
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.822
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
 0.821
ABO_0007
Histidinol-phosphatase, putatitve; Identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00213; Function unclear.
 
 0.739
djlA
dnaJ-like protein DjlA; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
 
    0.735
lptD
Conserved hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
     0.691
rpe
Ribulose-phosphate 3-epimerase; Identified by match to TIGR protein family HMMTIGR01740 InterPro: Ribulose-phosphate 3-epimerase; High confidence in function and specificity.
 
   
 0.686
surA
Survival protein surA precursor (Peptidyl-prolyl cis-trans isomerase surA); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
  
   0.643
algA
(mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
 0.596
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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