Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gdhAGlutamate dehydrogenase, fragment; (glutamate dehydrogenase) identified by sequence similarity; High confidence in function and specificity. (64 aa)    
Predicted Functional Partners:
gdhA-2
(glutamate dehydrogenase, NAD(P)-specific glutamate dehydrogenase) identified by sequence similarity; putative identified by match to PFAM protein families HMMPF02812 and HMMPF00208 InterPro: Glutamate/leucine/phenylalanine/valine dehydrogenase; High confidence in function and specificity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     0.969
gltB
Glutamate synthase, large subunit; Identified by sequencesimilarity; putative identified by match to PFAM protein family HMMPF04897 and HMMPF01645 InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity.
  
 
 0.805
aceF
Pyruvate dehydrogenase, E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.724
talB
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
    
 
 0.619
fadE-3
acyl-CoA dehydrogenase; Identified by match to PFAM protein family HMMPF00441 InterPro: Acyl-CoA dehydrogenase; High confidence in function and specificity.
  
 
 0.560
prpC
Methylcitrate synthase putative identified by sequence similarity; putative InterPro: Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family.
   
 0.440
sucA
(kgdA) (2-oxoglutarate dehydrogenase E1 component) identified by sequence similarity; putative InterPro: Dehydrogenase E1 component; High confidence in function and specificity.
   
 0.440
gltA
Citrate synthase; Identified by match to PFAM protein family HMMPF00285 InterPro: Citrate synthase; High confidence in function and specificity.
   
 0.440
cobB
Identified by match to PFAM protein family HMMPF02146 InterPro: Sir2 family; High confidence in function and specificity; Belongs to the sirtuin family. Class III subfamily.
    
 0.432
icdA
(icd) (isocitrate dehydrogenase NADP-dependentprokaryotic-type) identified by match to TIGR protein family HMMTIGR00183 InterPro: Isocitrate dehydrogenase NADP-dependent prok type; High confidence in function and specificity.
   
 0.424
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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