Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_2108(lipase/esterase family protein) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase/carboxlesterase family active site; High confidence in function and specificity. (316 aa)    
Predicted Functional Partners:
ABO_2107
(monooxygenase, putative) identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); High confidence in function and specificity.
    0.952
ABO_2109
(short chain dehydrogenase/reductase, putative) identified by sequence similarity; putative InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
    0.838
ABO_1097
Monooxygenase, flavin-binding family; Identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Family membership.
    0.656
estC
InterPro: Carboxylesterases type-B; High confidence in function and specificity.
 
   
 0.600
ABO_2106
(transcriptional regulator, putative) identified by match to PFAM protein family HMMPF00165 InterPro: AraC type helix-turn-helix; Family membership.
       0.555
ABO_1784
Non-ribosomal peptide synthase fragment, contains condensation, fatty-acid-CoA ligase and thioesterase domains. identified by sequence similarity; putative InterPro: AMP-dependent synthetase and ligase; Family membership.
   
 
 0.542
ABO_2393
Monooxygenase, flavin-binding family; Identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Family membership.
    0.531
ABO_0288
Monooxygenase flavin-binding family identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Function unclear.
 
    0.517
ABO_1197
Carboxylic ester hydrolases identified by sequencesimilarity; putative InterPro: Alpha/beta hydrolase fold; Family membership.
      
 0.482
ABO_1244
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF01118.
  
   0.423
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (44%) [HD]