STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_2120(Transcriptional regulator, putative) identified by match to PFAM protein family HMMPF02082 InterPro: Uncharacterized protein family UPF0074; Family membership. (143 aa)    
Predicted Functional Partners:
ABO_2119
Flavohemoprotein; (hmpA) identified by sequence similarity; putative InterPro: Globin flavohemoprotein (hemoglobin-like protein) (flavohemoglobin) (dihydropteridine reductase) (EC 1.6.99.7) (ferrisiderophore reductase b) (nitric oxide dioxygenase) (EC 1.14.12.17) (nod); High confidence in function and specificity; Belongs to the globin family.
 
   
 0.903
iscS
Cysteine desulfurase; Identified by sequence similarity; putative identified by match to PFAM potein family HMMPF00266; putative InterPro: Aminotransferase class-V; High confidence in function and specificity.
  
  
 0.734
nfuA
yhgI conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
  
 0.570
rrf2
Rrf2 family protein; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
  
   
 0.564
nnrS
Conserved hypothetical protein; NnrS protein. pfam05940, This family consists of several bacterial NnrS like proteins. NnrS is a putative heme-Cu protein and a member of the short-chain dehydrogenase family. Expression of nnrS is dependent on the transcriptional regulator NnrR, which also regulates expression of genes required for the reduction of nitrite to nitrous oxide, including nirK and nor. NnrS is a haem-and copper-containing membrane protein. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase.
 
  
 0.544
ABO_0670
Oxidoreductase (acting on iron-sulfur proteins as donors with NAD+ or NADP+ as acceptor) identified by sequence similarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership.
 
  
 0.446
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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