Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
cysI-2Sulfite reductase (NADPH); (cysI-2); identified by similarity to Pfam protein families PF01077 and PF03460; High confidence in function and specificity. (100 aa)    
Predicted Functional Partners:
cysJ
NADPH-sulfite reductase; Identified by sequence similarity. InterPro: FAD-binding domain; High confidence in function and specificity.
 
 
 0.993
cysI-1
Sulfite reductase (NADPH); Identified by similarity to Pfam protein families PF01077 and PF03460 InterPro: Nitrite and sulfite reductase; High confidence in function and specificity.
 
     0.946
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
 
  
 0.893
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
  
 0.838
cysC;
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
  
  
 0.800
ABO_2127
DsrE/DsrF-like family protein, Pfam:DrsE; Family membership.
       0.752
ABO_2128
Iron-sulfur binding domain protein.
       0.715
ABO_2129
Hypothetical protein.
       0.715
ABO_2130
2-nitropropane dioxygenase, putative; (conserved hypothetical protein) identified by sequencesimilarity; putative InterPro: 2-nitropropane dioxygenase; Family membership.
       0.715
sopT
(sopT; SAT) (Sulfate adenylatetransferase) (ATP-sulfurylase). identified by Glimmer2; InterPro: ATP-sulfurylase Pfam: ATP-sulfurylase; High confidence in function and specificity; Belongs to the sulfate adenylyltransferase family.
  
  
 0.561
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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