hflK protein (Alcanivorax borkumensis) - STRING interaction network

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Score

hflK

Protease subunit HflK; HflC and HflK could encode or regulate a protease. (390 aa)

Predicted Functional Partners:

hflC

0.999

ftsH

0.954

hflX

0.914

hfq

0.833

ABO_0096

0.729

miaA

0.722

yidC

0.574

hisZ

0.533

ABO_2199

0.525

purA

0.517

Your Current Organism:

Alcanivorax borkumensis

NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABO_0096	ftsH	ABO_0096	ABO_0322	SPFH domain/Band 7 family protein identified by sequence similarity; putative InterPro: Band 7 protein; Family membership.	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.827
ABO_0096	hflK	ABO_0096	ABO_2201	SPFH domain/Band 7 family protein identified by sequence similarity; putative InterPro: Band 7 protein; Family membership.	Protease subunit HflK; HflC and HflK could encode or regulate a protease.	0.729
ABO_2199	hflC	ABO_2199	ABO_2200	Hypothetical protein; Predicted by Glimmer/Critica.	Protease subunit HflC; HflC and HflK could regulate a protease.	0.522
ABO_2199	hflK	ABO_2199	ABO_2201	Hypothetical protein; Predicted by Glimmer/Critica.	Protease subunit HflK; HflC and HflK could encode or regulate a protease.	0.525
ABO_2199	hflX	ABO_2199	ABO_2202	Hypothetical protein; Predicted by Glimmer/Critica.	GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.	0.459
ABO_2199	hisZ	ABO_2199	ABO_2198	Hypothetical protein; Predicted by Glimmer/Critica.	ATP phosphoribosyl transferase regulatory subunit, putative; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.	0.800
ABO_2199	purA	ABO_2199	ABO_2197	Hypothetical protein; Predicted by Glimmer/Critica.	Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.678
ftsH	ABO_0096	ABO_0322	ABO_0096	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	SPFH domain/Band 7 family protein identified by sequence similarity; putative InterPro: Band 7 protein; Family membership.	0.827
ftsH	hflC	ABO_0322	ABO_2200	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Protease subunit HflC; HflC and HflK could regulate a protease.	0.947
ftsH	hflK	ABO_0322	ABO_2201	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Protease subunit HflK; HflC and HflK could encode or regulate a protease.	0.954
ftsH	hflX	ABO_0322	ABO_2202	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.	0.416
ftsH	hfq	ABO_0322	ABO_2203	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	0.431
ftsH	miaA	ABO_0322	ABO_2204	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.	0.430
ftsH	yidC	ABO_0322	ABO_2753	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Inner membrane protein, 60 kDa, putative; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.456
hflC	ABO_2199	ABO_2200	ABO_2199	Protease subunit HflC; HflC and HflK could regulate a protease.	Hypothetical protein; Predicted by Glimmer/Critica.	0.522
hflC	ftsH	ABO_2200	ABO_0322	Protease subunit HflC; HflC and HflK could regulate a protease.	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.947
hflC	hflK	ABO_2200	ABO_2201	Protease subunit HflC; HflC and HflK could regulate a protease.	Protease subunit HflK; HflC and HflK could encode or regulate a protease.	0.999
hflC	hflX	ABO_2200	ABO_2202	Protease subunit HflC; HflC and HflK could regulate a protease.	GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.	0.838
hflC	hfq	ABO_2200	ABO_2203	Protease subunit HflC; HflC and HflK could regulate a protease.	Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	0.818
hflC	hisZ	ABO_2200	ABO_2198	Protease subunit HflC; HflC and HflK could regulate a protease.	ATP phosphoribosyl transferase regulatory subunit, putative; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.	0.669