| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| clpX | hfq | ABO_1211 | ABO_2203 | ATP-dependent Clp protease, ATP-binding subunitClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.814 |
| clpX | ihfA | ABO_1211 | ABO_1836 | ATP-dependent Clp protease, ATP-binding subunitClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | Bacterial nucleoid DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.429 |
| csrA | dksA | ABO_1796 | ABO_0345 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.463 |
| csrA | dksA1 | ABO_1796 | ABO_1680 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | (DnaK suppressor protein homolog; C4-type zinc finger protein DksA/TraR family) identified by match to PFAM protein family HMMPF01258; Family membership. | 0.463 |
| csrA | hfq | ABO_1796 | ABO_2203 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.801 |
| csrA | ihfA | ABO_1796 | ABO_1836 | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | Bacterial nucleoid DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.744 |
| dksA | csrA | ABO_0345 | ABO_1796 | RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | 0.463 |
| dksA | hfq | ABO_0345 | ABO_2203 | RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.745 |
| dksA | ihfA | ABO_0345 | ABO_1836 | RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Bacterial nucleoid DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.405 |
| dksA1 | csrA | ABO_1680 | ABO_1796 | (DnaK suppressor protein homolog; C4-type zinc finger protein DksA/TraR family) identified by match to PFAM protein family HMMPF01258; Family membership. | Carbon storage regulator CsrA; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). | 0.463 |
| dksA1 | hfq | ABO_1680 | ABO_2203 | (DnaK suppressor protein homolog; C4-type zinc finger protein DksA/TraR family) identified by match to PFAM protein family HMMPF01258; Family membership. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.745 |
| dksA1 | ihfA | ABO_1680 | ABO_1836 | (DnaK suppressor protein homolog; C4-type zinc finger protein DksA/TraR family) identified by match to PFAM protein family HMMPF01258; Family membership. | Bacterial nucleoid DNA-binding protein; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.405 |
| hflC | hflK | ABO_2200 | ABO_2201 | Protease subunit HflC; HflC and HflK could regulate a protease. | Protease subunit HflK; HflC and HflK could encode or regulate a protease. | 0.999 |
| hflC | hflX | ABO_2200 | ABO_2202 | Protease subunit HflC; HflC and HflK could regulate a protease. | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.875 |
| hflC | hfq | ABO_2200 | ABO_2203 | Protease subunit HflC; HflC and HflK could regulate a protease. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.837 |
| hflC | miaA | ABO_2200 | ABO_2204 | Protease subunit HflC; HflC and HflK could regulate a protease. | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.751 |
| hflK | hflC | ABO_2201 | ABO_2200 | Protease subunit HflK; HflC and HflK could encode or regulate a protease. | Protease subunit HflC; HflC and HflK could regulate a protease. | 0.999 |
| hflK | hflX | ABO_2201 | ABO_2202 | Protease subunit HflK; HflC and HflK could encode or regulate a protease. | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.951 |
| hflK | hfq | ABO_2201 | ABO_2203 | Protease subunit HflK; HflC and HflK could encode or regulate a protease. | Host factor-I protein Hfg; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.847 |
| hflK | miaA | ABO_2201 | ABO_2204 | Protease subunit HflK; HflC and HflK could encode or regulate a protease. | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.806 |
