| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABO_0791 | nnrD | ABO_0791 | ABO_2208 | Identified by match to PFAM protein family HMMPF00293 InterPro: NUDIX hydrolase MuT motif proteins shown to be enzymes have been proposed to degrade compounds that are either deleterious to the cell or are normal metabolites present in excessive concentrations; Family membership. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.615 |
| ABO_2207 | amiB | ABO_2207 | ABO_2206 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | 0.853 |
| ABO_2207 | miaA | ABO_2207 | ABO_2204 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.677 |
| ABO_2207 | mutL | ABO_2207 | ABO_2205 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.638 |
| ABO_2207 | nnrD | ABO_2207 | ABO_2208 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.945 |
| ABO_2207 | queG | ABO_2207 | ABO_2209 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.623 |
| amiB | ABO_2207 | ABO_2206 | ABO_2207 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | 0.853 |
| amiB | miaA | ABO_2206 | ABO_2204 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.755 |
| amiB | mutL | ABO_2206 | ABO_2205 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.840 |
| amiB | nnrD | ABO_2206 | ABO_2208 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.896 |
| amiB | queG | ABO_2206 | ABO_2209 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.652 |
| cpn60; | mutL | ABO_0634 | ABO_2205 | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.475 |
| cpn60; | nnrD | ABO_0634 | ABO_2208 | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.753 |
| miaA | ABO_2207 | ABO_2204 | ABO_2207 | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | 0.677 |
| miaA | amiB | ABO_2204 | ABO_2206 | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | 0.755 |
| miaA | mutL | ABO_2204 | ABO_2205 | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.921 |
| miaA | nnrD | ABO_2204 | ABO_2208 | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.722 |
| miaA | queG | ABO_2204 | ABO_2209 | tRNA isopentenyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.452 |
| mutL | ABO_2207 | ABO_2205 | ABO_2207 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | 0.638 |
| mutL | amiB | ABO_2205 | ABO_2206 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | 0.840 |
