| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABO_1324 | queF | ABO_1324 | ABO_0880 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.490 |
| ABO_1324 | queG | ABO_1324 | ABO_2209 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.615 |
| ABO_2207 | amiB | ABO_2207 | ABO_2206 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | 0.853 |
| ABO_2207 | mutL | ABO_2207 | ABO_2205 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.638 |
| ABO_2207 | nnrD | ABO_2207 | ABO_2208 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.945 |
| ABO_2207 | queG | ABO_2207 | ABO_2209 | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.623 |
| acpD | queG | ABO_0027 | ABO_2209 | Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.631 |
| amiB | ABO_2207 | ABO_2206 | ABO_2207 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | 0.853 |
| amiB | mutL | ABO_2206 | ABO_2205 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.840 |
| amiB | nnrD | ABO_2206 | ABO_2208 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.896 |
| amiB | queG | ABO_2206 | ABO_2209 | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.652 |
| mutL | ABO_2207 | ABO_2205 | ABO_2207 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | 0.638 |
| mutL | amiB | ABO_2205 | ABO_2206 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | 0.840 |
| mutL | nnrD | ABO_2205 | ABO_2208 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.717 |
| mutL | queG | ABO_2205 | ABO_2209 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.557 |
| nnrD | ABO_2207 | ABO_2208 | ABO_2207 | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | (conserved hypothetical protein TIGR00150) identified by match to TIGR protein family HMMTIGR00150 InterPro: Uncharacterised P-loop hydrolase UPF0079. | 0.945 |
| nnrD | amiB | ABO_2208 | ABO_2206 | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | N-acetylmuramoyl-L-alanine amidase; Identified by sequencesimilarity; putative InterPro: Cell wall hydrolase/autolysin; High confidence in function and specificity. | 0.896 |
| nnrD | mutL | ABO_2208 | ABO_2205 | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.717 |
| nnrD | queG | ABO_2208 | ABO_2209 | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | Iron-sulfur cluster-binding protein, putative; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.831 |
| queA | queC | ABO_0500 | ABO_0762 | S-adenosylmethionine:tRNAribosyltransferase-isom e rase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | exsB protein, putative; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.569 |
